Ingestible beauty is a new and emerging category of skincare.
People are intrigued by the concept, and are keen to understand how collagen peptide supplements benefit the skin.
This page presents some key facts to help explain.
"In the gastrointestinal tract, most of the collagen peptides consumed are digested. With more than a 98% absorption rate, only a very small percentage will be passed out through the digestive system.” clarifies Tonja Lipp, Sr. Manager Business Development Health & Nutrition at Gelita, the manufacturer of VERISOL®.
"VERISOL® Bioactive Collagen Peptides® are a special mixture of bioactive collagen peptides. These peptide chains are very small compared to collagen molecules and are easily absorbed by the body."
In fact, a collagen supplement is not the consumption of collagen, it is actually the consumption of collagen peptides.
Collagen peptides are short chains of amino acids, in comparison to collagen itself which is a relatively long chain of amino acids. Collagen peptides are derived from collagen through a process called hydrolysis.
Almost 100% of the orally consumed VERISOL® collagen peptides are rapidly absorbed from the gastrointestinal tract. This is indicated by a pronounced increase of these peptides in blood plasma observed 15 to 30 minutes after consumption.1
Bioavailability studies show that collagen peptides could be detected in varying amounts in different organs and connective tissues, including the skin, after oral administration.2
The impact on the skin of ingested VERISOL® has also been studied in three double-blind, randomized, placebo controlled clinical trials.3
The clinical trials found that there was a clear demonstration of improved effects on the skin derived from the consumption of VERISOL® Bioactive Collagen Peptides®.
The first study in skin elasticity revealed that VERISOL® leads to an average of 7% increase in skin elasticity compared to a placebo treatment, and for women in the study aged 50 years and over, the increase in skin elasticity was 15% compared to a placebo treatment.
The second study showed a significant reduction of fine lines & wrinkles and that Pro-collagen Type I content was increased by 65% after 8 weeks of VERISOL® Bioactive Collagen Peptides® treatment compared to placebo.
The third study demonstrated that regular ingestion of VERISOL® over a period of 6 months led to a clear improvement of the skin in women suffering from moderate cellulite.
1. Iwai et al. 2005: Identification of food-derived collagen peptides in human blood aer oral ingestion of gelatin hydrolysates. J Agric Food Chem. 2005 Aug 10;53(16):6531-6.
2. Oesser S, Adam M, Babel W, Seifert J: Oral administration of (14)C labeled gelatin hydrolysate leads to an accumulation of radioactivity in cartilage of mice (C57/BL). J Nutr 1999;129:1891 – 1895
3. Proksch E, Segger D, Degwert J, Schunck M, Zague V, Oesser S: Oral Supplementation of Specic Collagen Peptides has Benecial Eects on Human Skin Physiology: A Double-Blind, Placebo-Controlled Study. Skin Pharmacol Physiol 2014;27:47-55
Proksch E, Schunck M, Zague V, Segger D, Degwert J, Oesser S: Oral Intake of Specic Bioactive Collagen Peptides Reduces Skin Wrinkles and Increases Dermal Matrix Synthesis. Skin Pharmacol Physiol 2014; 27:113-119.
Proksch E, Schunck M, Zague V, Oesser S: Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial Effect on Cellulite Morphology. Journal of Medicinal Food 18 (12) 2015, 1340–1348 DOI: 10.1089/jmf.2015.0022
"Pre-clinical trials with human skin fibroblasts have demonstrated, that not all collagen peptides have the same stimulatory effect," states Lipp.
"In vitro, the specific composition of VERISOL® Bioactive Collagen Peptides® triggered the highest expression of skin extracellular matrix."
The patented approach used in manufacturing VERISOL® delivers peptides that have been cleaved in a manner that the enzymatic function of the stomach is not capable of replicating.
This means that when consuming gelatin, it is highlly unlikely that your stomach will extract peptides from gelatin that will have the same characteristic properties and the same stimulatory effect on the skin as VERISOL®.
Further, in its unique peptide composition, VERISOL® Bioactive Collagen Peptides® have been shown to have a stimulatory effect on the skin that is superior in performance compared to other collagen supplements that have been created by alternative hydrolysis techniques.4
4. United States Patent Application (Pub. No.: US 2013/0252899 A1) COLLAGEN HYDROLYSATE FOR USE TO IMPROVE THE HEALTH OF HUMAN SKIN, HAIR AND/OR NAILS. Sep. 26, 2013
The Unique Characteristics of VERISOL
VERISOL® is produced through Gelita’s proprietary patented manufacturing processes.
The result of that manufacturing process is that VERISOL® is a collagen hydrolysate with a composition of at least 90% by weight of peptides with a molecular weight of less than 3,500 Da.
Moreover, VERISOL® comprises at least 45% by weight of four specifically characteristic peptides with a molecular weight between 600 and 1,200 Da.
The amino acid density of VERISOL® has a proportion of hydroxyproline of 12% or more by weight.
Gelita's manufacturing process delivers within VERISOL® a ratio of at least 50% of the N-terminal amino acids of the collagen hydrolysate being hydrophobic amino acids.