Superior Bioavailability
BERBEVIS® berberine phytosome delivers up to 10 times greater absorption on a molar basis compared with standard berberine, providing more systemic availability for metabolic and cardiovascular support.
Clinical Grade
Research shows BERBEVIS® supports healthy blood glucose, healthy lipid metabolism and cardiovascular markers in humans and preclinical studies.
BERBEVIS Phytosome®
Our capsules contain only BERBEVIS® berberine phytosome with ascorbyl palmitate, formulated for efficacy and tolerability.
The Clinical Evidence: BERBERINE
BERBEVIS supports healthy blood sugar balance by helping the body use carbohydrates for energy and manage glucose more efficiently. Clinical studies show berberine supplementation may:
- Improve fasting and post-meal blood sugar spikes
- Support insulin sensitivity
- Supports carbohydrate metabolism
In a small pilot, placebo-controlled clinical study of 36 adults with newly diagnosed type 2 diabetes mellitus, participants assigned to berberine supplementation showed improvements in markers related to fasting and post-meal blood glucose levels over several weeks (Yin et al., 2008).
Berberine assists in maintaining healthy cholesterol and triglyceride levels already within normal ranges and supports overall cardiovascular function, by helping maintain healthy blood lipid and blood glucose levels already within the normal range, which are important components of overall heart balance.
Clinical research suggests that berberine supplementation is associated with support for healthy LDL cholesterol and triglyceride levels within normal limits. Some studies also indicate support for maintaining healthy blood pressure levels already within the normal range when used alongside a balanced diet and healthy lifestyle (Zamani et al., 2022).
Research indicates BERBEVIS may support healthy body composition markers, including visceral fat reduction, when used as part of a balanced lifestyle.
A meta-analysis of 12 placebo-controlled trials involving 889 participants across various metabolic health populations reported that berberine supplementation supported favorable body composition markers, and demonstrated a safety profile comparable to placebo (Liu et al., 2025).
Support Your Daily Energy Production & Metabolic Health
Balanced Blood Glucose
Improved Craving Control
Maintain Healthy Blood Lipid
Berberine is used to support healthy blood sugar, heart health, maintain cholesterol levels in the normal range and overall metabolic wellness.
Berberine is used to support healthy blood sugar, heart health, maintain cholesterol levels in the normal range and overall metabolic wellness.
While results vary, some individuals may begin to notice improvements in general well-being after about 8 weeks of daily use. Taking this consistently along with a balanced diet and lifestyle, BERBEVIS® helps support healthy blood sugar already within the normal range and overall metabolic health, with additional benefits such as support for healthy cholesterol and lipid metabolism, potentially becoming more noticeable over time.
While results vary, some individuals may begin to notice improvements in general well-being after about 8 weeks of daily use. Taking this consistently along with a balanced diet and lifestyle, BERBEVIS® helps support healthy blood sugar already within the normal range and overall metabolic health, with additional benefits such as support for healthy cholesterol and lipid metabolism, potentially becoming more noticeable over time.
BERBEVIS®, also called phytosome berberine, uses a special technology that offers up to 10× better absorption than standard berberine, supporting consistent metabolic and cardiovascular wellness, while remaining gentle on the digestive system.
BERBEVIS®, also called phytosome berberine, uses a special technology that offers up to 10× better absorption than standard berberine, supporting consistent metabolic and cardiovascular wellness, while remaining gentle on the digestive system.
Berberine is sometimes referred to as “nature’s Ozempic” in media and online discussions, but the two are quite different and work through distinct mechanisms. While some evidence suggests that Berberine may modestly influence the body’s natural GLP-1 activity, its primary mode of action is the activation of AMPK, an enzyme that regulates cellular energy balance and metabolism.
In contrast, Ozempic is a prescription GLP-1 receptor agonist that directly mimics gut hormones to slow digestion and reduce appetite. Multiple clinical studies show that berberine helps support healthy glucose and lipid metabolism, making it a non-prescription option for metabolic health.
Berberine is sometimes referred to as “nature’s Ozempic” in media and online discussions, but the two are quite different and work through distinct mechanisms. While some evidence suggests that Berberine may modestly influence the body’s natural GLP-1 activity, its primary mode of action is the activation of AMPK, an enzyme that regulates cellular energy balance and metabolism.
In contrast, Ozempic is a prescription GLP-1 receptor agonist that directly mimics gut hormones to slow digestion and reduce appetite. Multiple clinical studies show that berberine helps support healthy glucose and lipid metabolism, making it a non-prescription option for metabolic health.
Standard berberine is known for poor oral bioavailability, which means only a small amount is absorbed into the bloodstream after digestion. As a result, higher doses are often used, which may increase the chance of digestive discomfort such as bloating, nausea, or changes in bowel habits in some individuals, sometimes referred to as "berberine belly".
Berberine phytosome is designed to improve absorption by binding berberine to naturally occurring lipids, and clinical research suggests it may offer significantly higher bioavailability (10x more) and be better tolerated than standard forms.
Standard berberine is known for poor oral bioavailability, which means only a small amount is absorbed into the bloodstream after digestion. As a result, higher doses are often used, which may increase the chance of digestive discomfort such as bloating, nausea, or changes in bowel habits in some individuals, sometimes referred to as "berberine belly".
Berberine phytosome is designed to improve absorption by binding berberine to naturally occurring lipids, and clinical research suggests it may offer significantly higher bioavailability (10x more) and be better tolerated than standard forms.
Most clinical studies on berberine examine use over about 3 to 6 months and suggest it is generally well tolerated over that period. In naturopathic and herbal practice, it is common to cycle berberine rather than use it continuously, with protocols such as 8 to 12 weeks on followed by a 2-to-4-week break.
This is a practical approach for people using berberine long-term and may help support tolerance and gut comfort. As with any supplement, the best schedule depends on your goals and how your body responds.
Most clinical studies on berberine examine use over about 3 to 6 months and suggest it is generally well tolerated over that period. In naturopathic and herbal practice, it is common to cycle berberine rather than use it continuously, with protocols such as 8 to 12 weeks on followed by a 2-to-4-week break.
This is a practical approach for people using berberine long-term and may help support tolerance and gut comfort. As with any supplement, the best schedule depends on your goals and how your body responds.
During perimenopause and menopause, shifting estrogen levels can affect fat distribution, insulin sensitivity and how the body uses energy, which is why many women notice stubborn midlife weight gain, especially around the abdomen.
Berberine may help support healthy metabolic function by activating AMPK, a key cellular energy pathway involved in glucose and lipid metabolism. In practical terms, that means it may help the body manage blood sugar and fat metabolism more efficiently, which can be useful during hormonal transitions and with age-related insulin resistance.
Berberine is not a hormone, but it can complement a healthy diet, movement and lifestyle plan for women seeking metabolic support in midlife.
During perimenopause and menopause, shifting estrogen levels can affect fat distribution, insulin sensitivity and how the body uses energy, which is why many women notice stubborn midlife weight gain, especially around the abdomen.
Berberine may help support healthy metabolic function by activating AMPK, a key cellular energy pathway involved in glucose and lipid metabolism. In practical terms, that means it may help the body manage blood sugar and fat metabolism more efficiently, which can be useful during hormonal transitions and with age-related insulin resistance.
Berberine is not a hormone, but it can complement a healthy diet, movement and lifestyle plan for women seeking metabolic support in midlife.